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Meanwhile, excessive NO co-transmission can be induced by toxic forms of both amyloid and tau, which in turn both remodels neurotransmission and amplifies nitrogen stress in ways that can feed into AD pathology (Wang et al., 2023)

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So if you could identify what the risk factors are for glaucoma, imagine if the paradigm was we're only going to treat it when your risk of blindness reaches 5%, which isn't triggered until you're old enough anyway