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[42] These microRNAs have been shown to regulate key neuronal genes involved in synaptic plasticity and neuroinflammation, further linking their dysregulation to cognitive decline in Alzheimer's patients
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That classification is separate from the compounding framework and reflects the current state of the evidence: a deep preclinical record, zero published human clinical trials, and a genuinely open question about how the animal model findings will translate when human studies eventually occur
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