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Both sleep length and quality are influenced by endocrine factors such as somatoliberin (growth hormone-releasing hormone),7 which contributes to slow-wave sleep8 — an indicator of healthy slumber.9 Some research suggests, though not conclusively, that DSIP can stimulate somatoliberin secretion,10 thereby promoting the onset of a deep stage of sleep

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6a), underwent stabilization upon AcrIF19 binding and inserted deeply into the catalytic channel, and interacted with the HD domain via Gln507 and the Gln511-Glu515 segment, as well as with the Linker domain via Gln493 and His496 (Fig