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The mucins are large complex proteins that are heavily covered by sugar molecules and that coat the gastric mucosal cells with a viscous, gel-like layer (also known as mucous)

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In a PDX model of colorectal cancer, it was found that the beneficial effect of MR may be through alteration of one-carbon metabolism flux, specifically in regard to redox and nucleotide balance that in combination with antimetabolite or radiation therapy, inhibits tumor growth [48]

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