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153 These findings indicate that itaconate functions both as a potent metabolic antimicrobial and as a driver of bacterial persistence
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In summary, CA demonstrates its anti-neuroinflammatory activities in the brain through modulating TNF- α , IL-1β, IL-6, and IFN-γ, suppressing the translocation of NF-kB p65 and increasing IL-10 and MCP-1 and activating Akt and ERK1/2 pathways
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