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6.3 Concomitant, sequential, and dual therapies Using four drugs (a PPI and three antibiotics) together during concomitant therapy is often referred to as “non-bismuth quadruple therapy.” A recent consensus conference organized by the Hellenic Society of Gastroenterology recommended that a non-bismuth quadruple regimen consisting of a PPI, AMO, CLA, and MET for at least 10 days should be the ideal first-line treatment in Greece, as it leads to higher H