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Lactate dehydrogenase (LDH) release and ATP levels confirmed these protective effects, showing a reduction in LDH release from 212.29% to 122.98% and restoring mitochondrial membrane potential to 94.62% at 50 μM of the puerarin-loaded PLGA nanoparticles
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In addition, the methionine salvage pathway, the glyoxalase system, carnitine metabolism, and remnants of the carboxylic acid metabolism were described in erythrocytes, and a recent review compiled a map of erythrocyte metabolism that listed 83 enzymes and membrane transport systems as well as 129 metabolites and ions [182]
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