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Why intramuscular delivery changes the math An oral B12 tablet is at the mercy of your digestion — stomach acid, gut health, age and certain medications all chip away at how much actually reaches your blood

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A typical FDA-approved regimen for pernicious anemia includes: • 100 µg IM/SC daily for 6–7 days • Then every other day for 7 doses • Then every 3–4 days for 2–3 weeks • Followed by 100 µg monthly for life Schedule follow-up and monitor progress Potassium levels should be monitored during the first 48 hours of treatment, as rapid red blood cell production may lead to hypokalemia and, rarely, sudden death