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The products of NAD + disassembly mediated by extracellular CD38, namely ADPR and NAM, may undergo further metabolic transformations [(e.g., to adenosine monophosphate (AMP) or adenosine (ADO)], particularly when co-expressed with other ectonucleotidases in certain pathological environments, such as the bone marrow (BM) niche (13)
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This team desensitized a 39-year-old vegetarian woman with vitamin B12 deficiency who, during approximately 10 months of intramuscular cyanocobalamin supplementation (1 injection
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