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High temperatures promote the decomposition of allicin into linear sulfides, such as DAMS, amd generate specific cyclic sulfides, such as vinyldithiin, through non-enzymatic pathways (Block, 1985)

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In contrast, increased Ca 2+ can promote depolarization of the mitochondria to induce autophagy and apoptosis [40, 84]

By facilitating the transport of fatty acids into the mitochondria