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Vitamin B12 deficiency – A 21st century perspective - PMC

There is also increasing evidence that deregulation of GSH synthesis contributes to the pathogenesis of diseases such as diabetes mellitus, pulmonary and hepatic fibrosis, alcoholic liver disease, cholestatic liver injury, endotoxemia, and drug-resistant tumors cells [10]

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So while it is produced naturally by the body, it can also be supplemented through oral, topical, or intravenous means to enhance its effects