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Thioredoxin Glutathione Reductase from Schistosoma mansoni: An Essential Parasite Enzyme and a Key Drug Target | PLOS Medicine

The copper component of GHK-Cu works through a different mechanism than pharmaceutical inhibitors

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Several molecules involved in the signal transduction processes, including small GTP-binding proteins and tyrosine kinases, such as c-Src, c-Yes, and protein kinase C (PKC), have been found to be localized at these tight junctions, presumably indicating their pivotal role in the maintenance of tight junction integrity 54,55