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Noncompartmental pharmacokinetic parameters were calculated from plasma drug concentration-time profiles by use of WinNonlin® software (Pharsight, Mountain View, CA, USA)
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Selenium administration partially reversed the amplitude of compound action potential, nerve conduction velocity, and the number of axons in rats receiving chemotherapy, which in turn had a moderate neuroprotective effect against cisplatin-induced neurotoxicity [107]
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