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When used as part of CagriSema, the dosing schedule looked like this in trials: Weeks 0–4: 0.25 mg cagrilintide + 0.25 mg semaglutide Weeks 4–8: 0.5 mg + 0.5 mg Weeks 8–12: 1 mg + 1 mg Weeks 12–16: 1.7 mg + 1.7 mg Week 16 onward: 2.4 mg + 2.4 mg (full maintenance dose) Until the medication is approved and prescribing information is finalized, any dosing decisions would only happen through participation in a clinical trial or, eventually, under the guidance of a healthcare provider

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doi: 10.1016/j.ensm.2018.05.003

allowing for maximum absorption and effectiveness