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[DOI] [PMC free article] [PubMed] [Google Scholar] Liu, C
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These adaptive dysfunction mechanisms occur within the compensatory anti-inflammatory response syndrome (CARS): active immunosuppression marked by lymphocyte depletion, sustained inhibitory receptor expression, tolerogenic antigen-presenting cell phenotypes, and profound intracellular signaling and epigenetic reprogramming mediated by oxidative stress [40,54,55,56]
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