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[24] describe additional dietary phytochemicals—such as curcumin, resveratrol, and quercetin—that promote ARE-dependent expression of protective enzymes, supporting the idea that diet-derived compounds may enhance cellular defenses through NRF2 signaling

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Excessive ROS may, however, have detrimental effects including modification of macromolecules such as nucleic acids, proteins and lipids (Kohen and Nyska, 2002)