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Molecular mechanisms of increased mucus secretion Secretion of mucins in the airway is continuous, with induced increases in mucin production intracellularly correlating to more concentrated mucin secretion, but secretagogues, such as ATP or histamine, are responsible for the rapid, complete release of granule contents accumulated within mucin-producing cells into the airway lumen (Jaramillo et al., 2018)

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Another study has unveiled that LDopa-treated PwPD who experienced cognitive impairment as measured through MMSE, had substantially lower serum Vit B12 levels in comparison to both LDopa-treated PD patients without cognitive deficits and the control group (Al Amin and Gupta 2023)