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6 Their work led to the development of three groups of ICIs that have been approved by the Food and Drug Administration US (FDA) for the treatment of several cancer types: PD-1 inhibitors (Nivolumab/Pembrolizumab/Cemiplimab), PDL-1 inhibitors (Atezolimumab/Durvalumab/Avelumab), and CTLA-4 inhibitor (Ipilimumab)
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