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Indeed, this disease is caused by the deficiency of the mitochondrial protein frataxin (FXN), triggered by the expansion of the guanine-adenine-adenine (GAA) triplet repeat in the first intron of the FXN gene on chromosome 9q21, which leads to its transcriptional inhibition through heterochromatinization and subsequent gene silencing [5-8]
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[DOI] [PubMed] [Google Scholar] 49.Şengel N., Köksal Z., Dursun A.D., Kurtipek Ö., Sezen Ş.C., Arslan M., Kavutçu M
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