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As an independent pathological entity, hyperuricemia extends beyond gout pathogenesis to contribute to systemic comorbidities, including atherosclerosis, chronic kidney disease, and metabolic syndrome

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Lajis et al., 2012, Menter, 2004, Monteiro et al., 2013, Navarrete-Solís et al., 2011, Niwano et al., 2018, Nordlund et al., 2006, Olejnik et al., 2018, Paine et al., 2001, Picardo and Carrera, 2007, Pires et al., 2018, Schulte et al., 2015, Tse, 2010