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Frataxin as a Kinetic Activator of Persulfide Transfer to ISCU Biochemical Assays Point to an Acceleration of Persulfide Transfer by Frataxin To establish the physiological function of FXN in Fe-S cluster biogenesis, the FDX2-based reaction was studied in a stepwise manner ( in vitro reconstitution of the complete mouse ISC machinery including FDX2 (FDX2-based reaction) showed that FXN accelerates the formation of [2Fe2S] clusters

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Pack Size:90 Capsules

2018 Sep;224(1):e13080