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10.1016/j.ebiom.2019.05.063 [DOI] [PMC free article] [PubMed] [Google Scholar] 654

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One could speculate that a key treatment strategy for progressive MS could involve targeting CNS-resident B cells, not aiming to suppress their traditional immunological (mis)behavior, but instead to quell a yet-to-be-discovered unconventional action, possibly related to secretion of an MS-specific myelin toxin into the CSF